Archive for November, 2008

The Mommy-Muse Features Dr. Dean Raffelock

Dr. Dean Raffelock, author of A Natural Guide to Pregnancy and Postpartum Health (Avery, 2002) was recently a guest on The Mommy-Muse radio show.  Search under ‘Content Library’ for his November 18th broadcast to hear A Natural Approach to Postpartum Recovery. 

 

A Natural Approach to Postpartum Recovery

Are you pregnant, have you just had a baby, or do you know a new mother? A woman expends enormous nutritional resources in the process of forming her baby’s body and giving birth. Many suffer symptoms such as mood swings, fatigue, worry, irritability, mental fog and sleep problems caused by nutritional depletion. draffelockphoto

Meet Dr. Dean Raffelock and Stephanie Raffelock. With their company, Sound Formulas, book and revolutionary products that provide the precise nutrients, vitamins, minerals, and essential oils that pregnant and postpartum mothers need, they are changing the paradigm of how new mothers are treated and can expect to feel. Dr. Elise Hewitt, a nationally-known pediatric chiropractor who was of great help to the Mommy-Muse and her baby, will also be stopping by. Discover how she helps children with conditions ranging from nursing difficulties, colic and poor sleep to asthma, ear infections and growing pains.

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Light Therapy Useful for Depression During Pregnancy

Even though this sample size of this pilot study was small (N=16), it shows a correlation between light exposure and major depression in pregnancy.  Keep in mind that this study focused on pregnant women with major depression, which is 5% of all pregnant women.  In general, the percentage of pregnant women with all types of depression is closer to 20 percent.

Light Therapy Useful for Depression During Pregnancy

Bright-light therapy may be an effective treatment for depression in pregnant women. The availability of an easy-to-use, potentially non-toxic antidepressant — light therapy — in pregnancy is a clinically attractive option.

The researchers conducted a pilot experiment to see whether exposure to bright light, a technique used to treat those suffering from seasonal affective disorder (SAD) or winter depression, might also work on women suffering from depression during pregnancy.

Around 5% of pregnant women meet the criteria for major depression.

However, doctors are often reluctant to prescribe antidepressant medications to pregnant women for fear of their effect on the fetus.

Previous research has suggested that bright light exposure may help people suffering from major depression or from postpartum depression. The exact mechanism has not been elucidated. Some data suggest that light therapy advances the timing of the daily biological clock, which may then bring about the antidepressant effect.

Sixteen pregnant women suffering from major depression completed the pilot study. They were instructed to expose themselves to an hour a day of bright ultraviolet light from a light box within 10 minutes of waking up for three to five weeks.

The patients showed a moderate improvement of their levels of depression after just three weeks of light treatment. For the seven women who underwent five weeks of light therapy, their average score on a scale that measures depression improved by 59%. When the light therapy was discontinued, the women showed signs of an increase in their levels of depression.

American Journal of Psychiatry April 2002;159:666-669

How Sunlight Can Improve Your Mental Health

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The association between darkness and depression is well known. Now a new study reveals the profound changes that light deprivation causes in your brain.

Neuroscientists kept rats in the dark for six weeks. The animals not only exhibited depressive behavior but also suffered damage in brain regions known to be underactive in humans during depression.

Further, neurons that produce norepinephrine, dopamine and serotonin, which are common neurotransmitters involved in emotion, pleasure and cognition, were observed in the process of dying. This neuronal death may be the mechanism underlying the darkness-related blues of seasonal affective disorder.

The dark-induced effects may stem from a disruption of the body’s clock. When an organism’s circadian system is not receiving normal light, that in turn might lead to changes in brain systems that regulate mood, the lead researcher said.

Sources:
Scientific American August 2008
Proceedings of the National Academy of Sciences March 25, 2008, vol. 105 no. 12 4898-4903

From www.mercola.com
Could Your Fatigue be Low Levels of a Simple Vitamin?

Perhaps you’re relying too heavily on caffeinated beverages to get you through the day. Or maybe you’re just suffering silently with that lack of ‘get-up-and-go’. Although there are many causes for fatigue, low levels of this simple vitamin may not only lead to a lack of energy, but also moodiness, nervousness, memory issues, and numerous other concerns.
Dr. Mercola’s Comments:
If you read Daily Sunlight Can Keep Cancer Away earlier this month, you know about the sun’s ability to prevent cancer. But what you may not know is that its influence on your mental health is just as profound.

When the rats in this study were deprived of light, cells in their brains that control emotions like pleasure as well as cognition began to die. In humans, these are also the brain regions that tend to be underactive if you are depressed, suggesting that without any exposure to light, it may be nearly impossible to feel happy.

Why You Need to Get Sunlight, Even as Fall and Winter Are Approaching

You are probably already familiar with seasonal affective disorder (SAD), which is depression that occurs during the fall and winter months when sunlight is scarce. An estimated 10 million to 12 million people in the United States alone suffer from SAD, while about 25 million Americans suffer from the “winter blues,” a condition not as serious as SAD but still requiring attention.

Both SAD and the winter blues are directly related to a lack of sunlight.

Serotonin (a chemical that helps regulate your mood) levels are low in people with depression and, at least one study has found, also in healthy people during the winter.

Since serotonin levels rise in your brain on days with a lot of sunlight, bright light may boost your mood by activating neurons in your brain that contain serotonin, leading to increased levels of the chemical in your brain, researchers say.

Serotonin neuron activity also tends to be higher on brighter days than darker days, even within the same season. This suggests that levels of serotonin in your brain are directly related to how much sunlight is available on any particular day.

In this most recent study, the researchers also pointed out similar findings.

“There is a high frequency of seasonal affective disorder in high latitudes where light exposure is limited, and bright light therapy is a successful antidepressant treatment,” the researchers said.

The take-home message here?

Getting minimal sunlight for prolonged periods of time can negatively impact your mood.

In most of the United States this tends to occur for a good portion of the fall, spring and winter, so a great number of people could be at risk of sunlight-related mood changes and even depression.

Your Body is Designed to be in the Sun

This is why most of us naturally feel like waking when the sun comes up, and sleeping when it’s dark. These inclinations are regulated by your body’s natural 24-hour cycle, or circadian rhythm, which has evolved over many years to align your physiology with your environment.

Your internal clock does much more than just help you sleep in the evening. Your body actually has many internal clocks — in your brain, lungs, liver, heart and even your skeletal muscles — and they all work to keep your body running smoothly by controlling temperature and the release of hormones, some of which impact your mood.

Your circadian rhythm, meanwhile, depends on receiving sunlight at the appropriate times (during the day) in order to function properly. If you do not get much sunlight when your body is expecting it — for example because you’re inside working all day or the weather is cold and cloudy — it can easily lead to changes in your brain that will negatively impact your mood.

For instance, melatonin, the “hibernation hormone,” increases with decreased light, which explains that tired feeling that comes on when it begins to get dark outside — even if it is only 4:00 in the afternoon.

How to Make Sure You Get the Light That Your Body Craves

In the summer, this is a no-brainer. Spend some time out in the sun. I’ve detailed just how long you should spend in the sun in my upcoming book Dark Deception, and also in this past article.

If you live in many areas of the United States, keep in mind that come late September till late March the sun is lower in the sky for most of the day, which means that a light-skinned person may need longer than 20 minutes in the sun each day, and a dark-skinned person could need one hour to 90 minutes to get all of the benefits of sunlight.

Remember, serotonin, the brain hormone associated with mood elevation, rises with exposure to bright light, and falls with decreased sun exposure. So during the winter months or on days when you can’t get outdoors, it’s really important to make up for this loss of bright light.

You can move to a more ideal climate for the winter but that is impractical for most. Fortunately, there’s a relatively easy way to make up for a lack of sunlight during the winter, and that’s by replacing the light bulbs in your home and office with full-spectrum versions that simulate the qualities of natural outdoor sunlight.

In order to achieve natural balanced sunlight indoors, your light bulbs must contain a full spectrum of color (imagine all the colors of the rainbow). Additionally, true full-spectrum lighting must contain infrared (IR) and ultraviolet (UV) wavelengths.

I have personally used full-spectrum lighting for years now, and can honestly say that they have provided an enormous boost in my ability to tolerate the often gloomy days where I live (near Chicago).

In fact, I have my entire home lit with these full-spectrum light bulbs.

I don’t consider them a replacement for real sunlight (nothing can do that), but they are the next best thing when the sun is not out, or when it’s too cold to spend time outdoors.

What Else Can You do to Boost Your Mood?

Sunlight is at the top of the list, but beyond that you can do the following to help improve your mood at any time during the year:

Optimize your diet using newly revised Take Control of Your Health nutrition guidelines, in combination with nutritional typing, to determine the foods you need to be eating, in the amounts you need to be eating them.

Pay particular attention to avoiding grains and sugar because of their specific effects on mood.

Have your vitamin D levels tested and get them to their optimal levels.

Get adequate exercise.

Taking a high-quality source of animal-based omega-3 fats such as krill oil.

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Study Links High Copper Levels to Postpartum Anxiety Reactions

 

After publishing Monday’s post on prenatal vitamins I became curious about copper. In the past I had supported a mother experiencing obsessive thoughts who had asked me about copper. Looking at various nutrients in prenatal vitamins reminded me of the possible link to copper and postpartum depression. As it turns out, I made an error regarding the level of copper in New Chapter Organics prenatals. This supplement contains .5mg of copper.

It is true, however that a link has been established between excess copper and postpartum mood disorders. It seems that high copper is evident in the more severe postpartum reactions, such as bipolar disorder, severe anxiety disorders, obsessive-compulsive disorder and psychosis.

Since I found this research from The Pfeiffer Treatment Center, I called and talked with their CEO, Scott Filer, MPH. Mr. Filer told me that copper levels are naturally elevated during pregnancy- they help infant’s blood vessels develop. At birth levels of copper are supposed to drop. It is possible that something, maybe poor levels of zinc, manganese, molybdenum, vitamin C and/or vitamin B6 prevent this drop and therefore cause excess copper-related postpartum mood disorders.

The Pfeiffer Treatment Center in Illinois is an integrative medical clinic providing both medical services and nutritional testing and support. Unfortunately, their protocol for excess copper is difficult during breastfeeding because the approach uses high levels of nutrients that have not been shown to be safe for use in breastfeeding women. Here is their research on copper and postpartum mood/anxiety issues:

New research sheds light on what may be an underlying cause of postpartum depression, and may help explain why some women suffer more extreme cases of PPD.

Researchers have identified a pattern of elevated copper levels in the blood of women with a history of the condition. “In our study, we looked at zinc and copper levels in 78 women who suffered from PPD after completed pregnancies, and compared them with a group of 148 mothers without a history of PPD, and also with a group of 28 non-depressed women,” said John Crayton, M.D. Dr. Crayton is a professor of psychiatry at Loyola University Stritch School of Medicine, Maywood, Ill. and the Section on Biological Psychiatry, Hines VA Hospital, Hines,
Ill.

Copper levels and copper to zinc ratios were significantly higher in the group of women with a
history of PPD compared to the other groups, according to the study published in the February issue of the Journal of Trace Elements in Medicine and Biology. “The exact nature of the association between elevated copper and PPD is not yet known, but copper plays a role in a variety of physiological systems that may be implicated in the development of PPD,” said William Walsh, PhD. Dr. Walsh is founder and director of research at the Pfeiffer Treatment Center and the Health Research Institute, Warrenville, Ill., and a coauthor of the study. Walsh added that elevated copper in the brain tends to diminish dopamine and increase norepinephrine levels.

“Zinc and copper play important roles in brain chemistry and are present in high concentrations in the brain’s hippocampus which is involved in mood regulation, short-term memory, and behavior control,” Dr. Crayton said.
During the nine months of a normal pregnancy, blood copper levels increase more than 100% but
quickly return to normal after birth. This study indicates that the high copper condition can
persist for many years in PPD women.

“We have seen dramatic improvement in women with PPD when we treat them with supplements that lower copper levels and restore a normal copper to zinc ratio,” said Dr. Walsh.

“The next step is a controlled, clinical trial to verify these results, which may lead to a more effective treatment for PPD.
Does Your Multivitamin Contain Copper? An article from www.mercola.com

Older people whose diets are heavy in copper, saturated fats and trans fats experienced a faster rate of mental decline.

A six-year study of more than 3,700 people aged 65 or older showed that those who consumed at least 1.6 milligrams of copper a day, along with high levels of saturated and trans fats, added almost 20 years to their ages in terms of mental decline. The U.S. daily recommended intake of copper is 0.9 milligrams.
Too much copper in the blood could block the body’s ability to destroy the proteins that form the plaques found in the brains of Alzheimer’s patients. Copper has been found at high levels in the blood of Alzheimer’s patients.

Many of those in the study with high copper levels took multivitamins containing the mineral.

Sources:
Archives of Neurology August 2006; 63(8): 1085-1088
New York Times August 22, 2006
Scientific American.com August 14, 2006

According to nutritionist Blake Graham, copper is an essential mineral with a number of important
functions. Copper is involved in energy production, connective tissue formation, gene expression, neurotransmitter synthesis and metabolism, melanin formation, the formation and maintenence of myelin, and antioxidant function. It also interacts with iron, zinc, fructose and vitamin C. While copper deficiency is relatively rare, copper excess (hypercupremia) is surprisingly common.

Excess copper is predominantly a condition present in women. For example in women diagnosed with major depression 45% have excess copper levels while only 3% of men with major depression have excess copper. (Pfeiffer Treatment Center data) This gender difference is due to estrogen causing an elevation of copper levels.

Excess copper seems to be related to tinnitus (ringing in the ears), frontal headaches, learning or speech impairments, skin sensitivity to metals, difficulty falling asleep, negative reactions to estrogen (e.g. oral contraceptives/HRT), and negative reactions to nutritional supplements containing copper.

Mood symptoms related to excess copper include anxiety/agitation, temper tantrums, hyperactivity, PMS, and depression-, including premenstrual and postpartum depression (Pfeiffer Treatment Center data).

Copper excess risk factors:

Pregnancy
Presently taking estrogen containing medication (e.g. OCP, HRT)
Currently take multivitamin containing copper
Regularly use copper tea kettles or pans
Blue-green stains in bathtub, toilet or sink (suggestive of elevated copper content of water)

Family history of:

Postpartum depression
ADD/ADHD/Autism
Wilson’s Disease

There are a number of different laboratory tests available to assess copper levels. Unfortunately a great many people are being diagnosed with excess copper when this is actually not the case. For example most people who have had a hair analysis done prior to seeing me have been told they have excess copper levels. Copper levels in hair are claimed to correlate with copper levels in the liver and other tissues. However one detailed study found hair copper levels did not correlate with copper levels in the liver, heart, muscle, kidney, aorta and rib. (Aalbers & Houtman. 1985) The other problem with relying solely on hair levels is that hair is subjected to external contamination and laboratories vary significantly in terms of accuracy and reference ranges.

I only recommend Doctors Data Inc. for hair analysis. It is recommended that a person wash their hair with Johnson’s baby shampoo for 2 weeks prior to hair collection to minimize hair contamination.

“Hair analysis ALONE is a very poor way to assess copper status. I say this after (a) evaluating more than 100,000 hair analyses, (b) developing the first high-quality hair standards (loaned to NIH and other researchers), and (c) performing numerous double-blind, controlled experiments involving hair chemistries. Findings of high Cu levels in hair are compromised by the many external sources of Cu which cannot be completely removed by washing. Low levels of Cu in hair and/or blood often are coincident with dangerous overloads of Cu in liver. Hair Cu values can provide information of clinical significance, but by itself is not clinically decisive.”, Bill Walsh, PhD, Pfeiffer Treatment Center.

According to Walsh copper contamination comes from water, “… hair gels/dyes/etc, and exposure to pools/jacuzzis treated with copper sulfate to kill algae.”
Also hair reflects excretion (not tissue burden), so those with high copper in hair may simply be the efficient excretors, not those with elevated levels.

For example according to Walsh:
“… low hair levels of Cu can occur in situations involving Cu overload. A good example is Wilson’s Disease in which hair, blood, and urine Cu levels can be extremely low in a person who may be dying of Cu overload in liver.”

Dr. William Walsh of the Pfeiffer Treatment Center and copper expert believes that the best way to diagnose excess copper levels are from measuring both copper and ceruloplasmin (copper binding protein) in serum (blood levels). From these two levels the percentage free copper in serum can be calculated.

According to Walsh:
Percentage free copper above 25% is classified as elevated.

Serum copper of 17.5 – 20.0 umol/L (110 – 125 ug/dL) is classified as high-normal and serum copper above 20 umol/L (125 ug/dL) is classified as high.

Treatment:

The basis of copper lowering treatment is using nutrients which reduce copper levels. These are zinc, manganese, molybdenum, vitamin C and vitamin B6. Water filtration is recommended to minimize copper intake from water. Avoiding copper containing supplements is also suggested.

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Guest Author Series: Dr. Dean Raffelock and Dr. Hyla Cass

To read this post online, click the title above…

An Integrative Approach to the Prevention and Treatment of Postpartum Depression
Dean Raffelock, D.C., Dipl.Ac./L.Ac, CCN, DIBAK
Hyla Cass, M.D.

Dean Raffelock D.C., Dipl. Ac./ L.Ac, CCN, DIBAK is a doctor of chiropractic and has earned board certifications in acupuncture, clinical nutrition, and applied kinesiology. He is the lead author of the book A Natural Guide to Pregnancy and Postpartum Health (Avery, 2003). Dr. Raffelock has a holistic practice in Boulder, Colorado. He is Vice President of Research and Development for Sound Formulas, LLC, a nutritional company dedicated to helping pregnant and new mothers receive optimal nutrition before, during, and after giving birth. For more information, see his website: www.pregnancyrecovery.com.

Hyla Cass, M.D. is a board-certified psychiatrist, former Assistant Clinical Professor of Psychiatry at UCLA School of Medicine, and author of several books, including Natural Highs, 8 Weeks to Vibrant Health, and Supplement Your Prescription. A member of the Medical Advisory Board of the Health Sciences Institute and Taste for Life Magazine, she is also Associate Editor of Total Health and served on the board of California Citizens for Health. Dr. Cass has also served as president of Vitamin Relief USA (www.vrusa.org). She has a clinical practice of integrative medicine and psychiatry in Pacific Palisades, CA. For more information, see her website: www.drcass.com.

Postpartum depression (PPD) has become a national epidemic in the United States, affecting 15%-20% of all new mothers, or about 600,000-800,000 women annually. (1) It is now estimated that over 30 million Americans are on antidepressant or anti-anxiety medications. (2) The majority of this 30 million are women who have one or more children. The chance of suffering from PPD increases with each successive child. (3)
The most common medical treatment for PPD is SSRI (selective serotonin reuptake inhibitors) antidepressant drugs.

Combination reuptake inhibitors for both serotonin and norepinephrine (SNRIs) are also commonly used. In the case of postpartum psychosis, antipsychotic drugs are used and are necessary. Many women are now given samples of SSRIs as they are leaving the maternity ward. Most medical sources believe that PPD is caused by an imbalance of brain chemistry and that pharmaceutical intervention is the treatment of choice. While a certain percentage of women suffering from PPD may need pharmaceutical assistance, these are far fewer than are actually receiving them.

The most common symptoms of PPD include the following:

1. Persistent feelings of despair and/or anxiety;
2. Loss of energy and low levels of daily functioning;
3. Sleep and eating disturbances;
4. Inability to focus, concentrate or make decisions;
5. Feelings of worthlessness, shame and guilt;
6. Feelings of indifference and/or resentment towards the baby;
7. Intrusive negative thoughts and/or obsessive worries–in the most serious cases, this includes thoughts of harming oneself or the baby;
8. Reduced sex drive;
9. Loss of joy and appreciation for life;
10. Irritability or excessive anger.

The literature generally outlines several types of postpartum disorders that have special features beyond the typical symptoms of depression. These include:

1. Postpartum Anxiety Disorder. Here, the primary symptoms are excessive nervousness, hyper-vigilance, racing thoughts and in some cases outright panic. Panic attacks are especially frightening–sufferers often believe they are dying, as they experience shortness of breath, dizziness and a pounding chest.

2. Postpartum Obsessive-Compulsive Disorder. Most often, this takes the form of obsessive thoughts or worries about the baby and may be accompanied by compulsive behaviors such as constantly checking if the baby is breathing, constantly washing to protect the baby from germs, etc. The most disturbing type of obsessive thoughts are those in which the mother envisions harming her baby in some way. These thoughts are unwanted, intrusive and terrifying to the mother. It is important to emphasize that, except in extremely rare instance of psychosis (see below), these thoughts are not accompanied by any actions. Nonetheless, the mother may be so frightened by her own thoughts that she avoids the baby and consequently neglects her. It is terribly difficult for new mothers to acknowledge having such thoughts, and as a result, many suffer in isolation.

3. Post-traumatic Stress Disorder. PTSD can occur in response to a real or perceived traumatic childbirth or because of unresolved past trauma–sometimes sexual in nature–triggered during childbirth. A woman who experiences PTSD is likely to have recurring, memories, dreams or even flashbacks of the traumatic labor/birth. She will be hyper-vigilant and startle easily, and will likely suffer from sleeplessness, irritability, poor concentration and apathy. Women who have experienced a particularly traumatic childbirth often show symptoms of both PTSD and PPD.

4. Postpartum Psychosis. This is the most extreme and rarest of all postpartum disorders. When it occurs, the mother loses touch with reality and her symptoms may include extreme disorientation (e.g., not knowing who she is), delusional or paranoid thinking, and visual or auditory hallucinations. The few, tragic cases where mothers have harmed their children while in a psychotic state have received enormous media attention. As a result, many people inaccurately associate PPD with psychotic symptoms and dangerous behavior. This constitutes yet another reason why women fail to get help–they want to avoid being labeled with such a stigmatized disorder.

Article Premise Overview: Foundations of A Nutritional Approach to PPD
The human body is entirely formed from nutrients. Every muscle, organ, gland, bone, cell, and fluid is composed entirely of nutrients (environmental toxins notwithstanding). All of the neurotransmitters, hormones, biochemical structures, and metabolic pathways are formed from nutrients.

There is no other normal physiological process that drains more nutrients than pregnancy, giving birth, and caring for a new infant which may include breastfeeding. The fact that a mother’s body donates all the nutrients required to form her baby’s body is too often overlooked when it comes to the medical treatment of PPD. Not only does the placenta literally rob the mother’s body of all the key nutrients required to make another human being, but the placenta itself is formed from nutrients taken from the mother’s body.
Other factors that may contribute to a drain of a new mother’s nutrient reserves are sleep deprivation, breastfeeding, returning to work, and the extra energy required to take care of an infant and integrate a new baby into her family. If a pregnant woman’s or new mother’s nutrient reserves are too low, she is much more vulnerable to experiencing PPD because all of the body’s normal metabolic processes are entirely dependent upon nutrients.

Rarely is there is any mention that the body’s production of neurotransmitters is completely dependent upon their nutritional precursors. (4) Nor are the causes of these nutritional precursor deficiencies discussed. Additionally, the reciprocal relationship between hormone and neurotransmitter production is rarely taken into consideration by most physicians when considering treatment for PPD. The nutritional requirements of mitochondrial function, the importance of liver function from Western and Eastern perspectives, and some individual nutrients like Omega 3 fish oils, L-theanine, SAMe, inositol, and the herb St. John’s Wort can also be of great assistance in treating PPD. These will be briefly discussed.

An integrative approach to treating PPD may include nutritional therapies, bio-identical hormone replacement, moderate exercise, a nutrient dense diet, proper rest, psychological counseling/support, stress reduction techniques, elimination of caffeine, alcohol and other addictive drugs, and if needed, pharmaceutical intervention.

Neurotransmitter Nutritional Precursors

Serotonin and Tryptophan

The amino acid L-Tryptophan is required for the body to produce serotonin. Ninety-five percent of the serotonin in the human body is produced in the intestinal tract. Approximately five percent is produced in the brain. The serotonin produced in the intestinal tract is unavailable to the brain because serotonin cannot pass through the blood- brain barrier. L-Tryptophan also does not easily pass through the blood-brain barrier and requires a carrier protein to ferry it into the brain. The consumption of simple sugars changes brain neuron cell membrane amino acid selectivity, allowing tryptophan to enter the brain more easily. Hence, the craving sweets is often a sign of serotonin deficiency.

Serotonin has been referred to as the brain’s mood elevating and tranquilizing chemical. Inadequate serotonin levels are linked with depression, anxiety, insomnia, irritability, and weight gain. Serotonin mediated depression usually contains an element of anxiety. Serotonin is considered an inhibitory neurotransmitter. Its functions include:

§ Inhibiting Glutamate excitability over diverse regions of the CNS
§ Stimulating its own receptors on GABA neurons prompting GABA to perform its inhibitory function
§ Inhibiting the release of the Catecholamines: Dopamine, Norepinephrine, and Epinephrine.
A comparison of the effects of optimal serotonin levels to low serotonin levels to reveals the following contrasts:

1) Hopeful/optimistic—————-Depressed
2) Calm—————————Anxious
3) Good-natured——————–Irritable
4) Patient————————–Impatient
5) Reflective/ thoughtful————–Impulsive/Reactive
6) Loving /Caring——————–Abusive
7) Able to concentrate—————-Short attention span
Creative/focused——————Blocked/scattered
9) Moderate carbohydrate intake——–Excessive carbohydrate intake
10) Good sleep and dream recall——–Insomnia and poor dream recall

Tryptophan is converted to its metabolite, 5- Hydroxy-Tryptophan (5-HTP) which is then converted to serotonin. Niacin, iron, and folic acid are required for L-Tryptophan to be converted into 5-HTP. The body also requires pyridoxal-5-phosphate along with 5-HTP in order to produce serotonin. Magnesium and riboflavin (B2) are required for the conversion of pyridoxine (B6) into pyridoxal-5-phosphate. Deficiencies in any of these nutrients can limit the production of serotonin. Numerous double-blind studies have shown 5-HTP to be as effective as antidepressant drugs with fewer and milder side effects and most times better tolerated. (5-11)

 

from Dr. Marty Hinz neurotransmitter seminar

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